Sungkyunkwan University’s Nano Engineering research team announced on October 13th that they have developed a technology that can quickly remove the tumor by transforming the micro-environment near the cancer cell. This is done by implanting a transporter that contains immunomodulation substance. The result of the research was published in the world renowned journal “Advanced Materials”.
The human body has immunocytes that suppress the development of cancer but also other immunocytes that expedite the metastasis of cancer cells. Therefore, immune-oncology is only effective to a limited group of patients.
The research team created a transporter loaded with chemical anti-cancer drug and immunomodulation substance. They maximized its efficiency by controlling the immunocytes of cancer cells while transmitting just enough anti-cancer drug to the tumor to prevent the excessive use of drug.
The team made a 5~10mm big transporter in a shape of a pill. The injected the transporter to a rat with breast and cervical cancer to examine the prevention of cancer cell. Group of rats that took the pill survived after the surgery but rats that only took immuno-oncology died after a month.
Professor Yongtaek LIM said, “We expect to maximize the effect by loading a customized drug after the analysis of immunosuppressive agent of each patient”.
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